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Article

Glutamate utilization couples oxidative stress defense and the tricarboxylic acid cycle in Francisella phagosomal escape.

PLoS pathogens - 1 Jan 2014

Ramond Elodie, Gesbert Gael, Rigard Mélanie, Dairou Julien, Dupuis Marion, Dubail Iharilalao, Meibom Karin, Henry Thomas, Barel Monique, Charbit Alain

Abstract excerpt

Intracellular bacterial pathogens have developed a variety of strategies to avoid degradation by the host innate immune defense mechanisms triggered upon phagocytocis. Upon infection of mammalian host cells, the intracellular pathogen Francisella replicates exclusively in the cytosolic compartmen...

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Identifiers

PMID: 24453979
DOI: 10.1371/journal.ppat.1003893
PMCID: PMC3894225

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24453979-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Glutamate utilization couples oxidative stress defense and the tricarboxylic acid cycle in Francisella phagosomal escape.PMID 24453979Read ↗

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