Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Francisella tularensis pathogenicity island protein essential for bacterial proliferation within the host cell cytosol.

Cellular microbiology - 1 Oct 2007

Santic Marina, Molmeret Maelle, Barker Jeffrey R, Klose Karl E, Dekanic Andrea, Doric Miljenko, Abu Kwaik Yousef

Abstract excerpt

Francisella tularensis is an intracellular bacterial pathogen, and is a category A bioterrorism agent. Within quiescent human macrophages, the F. tularensis pathogenicity island (FPI) is essential for bacterial growth within quiescent macrophages. The F. tularensis-containing phagosome matures to a late endosome-like stage that does not fuse to lysosomes for 1-8 h, followed by gradual bacterial escape into the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytosol
Share to Francisella tularensis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomic Islands

Share to Phagosomes

Share to Spleen

Share to Superinfection

Share to Tularemia

Source

Identifiers

PMID: 17517064
DOI: 10.1111/j.1462-5822.2007.00968.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Francisella tularensis pathogenicity island protein essential for bacterial proliferation within the host cell cytosol.PMID 17517064Read ↗

The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm.Semantic proximity Read ↗

IglG and IglI of the Francisella Pathogenicity Island Are Important Virulence Determinants of Francisella tularensis LVSSemantic proximity Read ↗

Cell biology and molecular ecology of<i>Francisella tularensis</i>Semantic proximity Read ↗

Disruption of Francisella tularensis Schu S4 iglI, iglJ, and pdpC genes results in attenuation for growth in human macrophages and in vivo virulence in mice and reveals a unique phenotype for pdpC.Semantic proximity Read ↗

Molecular bases of proliferation of Francisella tularensis in arthropod vectorsSemantic proximity Read ↗

Modulation of biogenesis of the Francisella tularensis subsp. novicida-containing phagosome in quiescent human macrophages and its maturation into a phagolysosome upon activation by IFN-gamma.Semantic proximity Read ↗

Uncovering the components of the Francisella tularensis virulence stealth strategy.Semantic proximity Read ↗

Host Factors Required for Modulation of Phagosome Biogenesis and Proliferation of Francisella tularensis within the CytosolSemantic proximity Read ↗

The Francisella tularensis LVS ΔpdpC mutant exhibits a unique phenotype during intracellular infection.Semantic proximity Read ↗

Exploitation of Host Cell Biology and Evasion of Immunity by Francisella TularensisSemantic proximity Read ↗

Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway.Semantic proximity Read ↗

The Francisella pathogenicity island protein PdpD is required for full virulence and associates with homologues of the type VI secretion system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.