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Article

A protein complex that regulates PtdIns(3,5)P2 levels.

The EMBO journal - 21 Jan 2009

Michell Robert H, Dove Stephen K

Abstract excerpt

Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) is needed for retrograde membrane trafficking from lysosomal and late endosomal compartments and its synthesis is tightly regulated. But how cells regulate PtdIns(3,5)P2 synthesis--for example, in response to hyperosmotic shock--remains unexplained. A paper from the Weisman group gives the most complete picture so far of a multiprotein complex that controls...

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Source

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Identifiers

PMID: 19158662
DOI: 10.1038/emboj.2008.270
PMCID: PMC2634735

Genes

VAC14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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