Article

The Phosphoinositide 5-Phosphatase inpp5k: From Gene Structure to <em>in Vivo</em> Functions

2020-09-17

Abstract excerpt

INPP5K (Inositol Polyphosphate 5-Phosphatase K, or SKIP (for Skeletal muscle and Kidney enriched Inositol Phosphatase) is a member of the phosphoinositide 5-phosphatases family. Its protein structure is comprised of a N-terminal catalytic domain which hydrolyses both PtdIns(4,5)P2 and PtdIns(3,4,5)P3, followed by a SKICH domain at the C-terminus which is responsible for protein-protein interactions and subcellular...

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Literature Corpus work: 9518dc5b-0193-5d2e-9542-51b2ad95d616
DOI: 10.20944/preprints202009.0399.v1

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