Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry.

doi:10.1158/0008-5472.CAN-07-3239

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Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry.

Cancer research - 1 Dec 2007

Poynter Jenny N, Figueiredo Jane C, Conti David V, Kennedy Kathleen, Gallinger Steven, Siegmund Kimberly D, Casey Graham, Thibodeau Stephen N, Jenkins Mark A, Hopper John L, Byrnes Graham B, Baron John A, Goode Ellen L, Tiirikainen Maarit, Lindor Noralane, Grove John, Newcomb Polly, Jass Jeremy, Young Joanne, Potter John D, Haile Robert W, Duggan David J, Le Marchand Loic

Abstract excerpt

Recent publications have reported that common variants on 8q24 are associated with both prostate and colorectal cancers (CRC). In addition, one of these studies (the ARCTIC study) initially observed an association with a single nucleotide polymorphism (SNP) on 9p24 that was not confirmed in some of their validation data sets. In the research described here, we conducted a case-unaffected sibling analysis using...

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PMID: 18056436
DOI: 10.1158/0008-5472.CAN-07-3239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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