Article
Novel single nucleotide polymorphism associations with colorectal cancer on chromosome 8q24 in African and European Americans.
Carcinogenesis - 1 Aug 2009
Kupfer Sonia S, Torres Jada Benn, Hooker Stanley, Anderson Jeffrey R, Skol Andrew D, Ellis Nathan A, Kittles Rick A
Abstract excerpt
Regions on chromosome 8q24 harbor susceptibility alleles for multiple cancers including colorectal (region 3) and prostate cancer (regions 1-4). The objectives of the present study were (i) to test whether single-nucleotide polymorphisms (SNPs) in region 4 are associated with colorectal cancer (CRC) in European or African Americans; (ii) to test whether 8q24 SNPs previously shown to be associated with colorectal...
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