Article
Genetic variation in 8q24 associated with risk of colorectal cancer.
Cancer biology & therapy - 1 Jul 2007
Gruber Stephen B, Moreno Victor, Rozek Laura S, Rennerts Hedy S, Lejbkowicz Flavio, Bonner Joseph D, Greenson Joel K, Giordano Thomas J, Fearson Eric R, Rennert Gad
Abstract excerpt
Chromosome 8q24 harbors oncogenes known to be involved in pathogenesis of colorectal cancer (CRC) as well as uncharacterized genetic variants that have recently been shown to influence inherited risk of prostate cancer. In a population-based case-control study of colorectal cancer in northern Israel, we investigated the association between variation in 8q24 and risk of CRC. Among 1,861 incident cases and 1,937...
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