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Article

Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk.

Human molecular genetics - 1 Sept 2008

Berndt Sonja I, Potter John D, Hazra Aditi, Yeager Meredith, Thomas Gilles, Makar Karen W, Welch Robert, Cross Amanda J, Huang Wen-Yi, Schoen Robert E, Giovannucci Edward, Chan Andrew T, Chanock Stephen J, Peters Ulrike, Hunter David J, Hayes Richard B

Abstract excerpt

Several different genetic variants at chromosome 8q24 have been related to prostate, breast and colorectal cancer risk with evidence of region-specific risk differentials for various tumor types. We investigated the association between 15 polymorphisms located in 8q24 regions associated with cancer risk in a pooled analysis of 2587 colorectal adenoma cases, 547 colorectal cancer cases and 2798 controls of...

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Adenoma
Aged
Chromosomes, Human, Pair 8
Colorectal Neoplasms
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 18535017
DOI: 10.1093/hmg/ddn166
PMCID: PMC2561994

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