Association of 8q24.21 loci with the risk of colorectal cancer: a systematic review and meta-analysis.

doi:10.1111/j.1440-1746.2011.06831.x

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Article

Association of 8q24.21 loci with the risk of colorectal cancer: a systematic review and meta-analysis.

Journal of gastroenterology and hepatology - 1 Oct 2011

Haerian Monir Sadat, Baum Larry, Haerian Batoul Sadat

Abstract excerpt

BACKGROUND AND AIM: Recent genome-wide association studies of colorectal cancer (CRC) have identified rs6983267 and trs10505477 polymorphisms as key loci in the 8q24 region to be associated with CRC. In the present study, we performed a meta-analysis to determine whether these loci are risk factors for susceptibility to CRC. METHODS: We meta-analyzed the 22 included studies (47 003 cases and 45 754 controls) that...

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PMID: 21722176
DOI: 10.1111/j.1440-1746.2011.06831.x

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