Article
Selective genotyping and phenotyping strategies in a complex trait context.
Genetics - 1 Apr 2009
Sen Saunak, Johannes Frank, Broman Karl W
Abstract excerpt
Selective genotyping and phenotyping strategies are used to lower the cost of quantitative trait locus studies. Their efficiency has been studied primarily in simplified contexts--when a single locus contributes to the phenotype, and when the residual error (phenotype conditional on the genotype) is normally distributed. It is unclear how these strategies will perform in the context of complex traits where...
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