Article
Selective phenotyping for increased efficiency in genetic mapping studies.
Genetics - 1 Dec 2004
Jin Chunfang, Lan Hong, Attie Alan D, Churchill Gary A, Bulutuglo Dursun, Yandell Brian S
Abstract excerpt
The power of a genetic mapping study depends on the heritability of the trait, the number of individuals included in the analysis, and the genetic dissimilarity among them. In experiments that involve microarrays or other complex physiological assays, phenotyping can be expensive and time-consuming and may impose limits on the sample size. A random selection of individuals may not provide sufficient power to...
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