Article
Sequential quantitative trait locus mapping in experimental crosses.
Statistical applications in genetics and molecular biology - 1 Jan 2007
Satagopan Jaya M, Sen Saunak, Churchill Gary A
Abstract excerpt
The etiology of complex diseases is heterogeneous. The presence of risk alleles in one or more genetic loci affects the function of a variety of intermediate biological pathways, resulting in the overt expression of disease. Hence, there is an increasing focus on identifying the genetic basis of disease by systematically studying phenotypic traits pertaining to the underlying biological functions. In this paper...
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