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Article

Quantitative trait locus study design from an information perspective.

Genetics - 1 May 2005

Sen Saunak, Satagopan Jaya M, Churchill Gary A

Abstract excerpt

We examine the efficiency of different genotyping and phenotyping strategies in inbred line crosses from an information perspective. This provides a mathematical framework for the statistical aspects of QTL experimental design, while guiding our intuition. Our central result is a simple formula that quantifies the fraction of missing information of any genotyping strategy in a backcross. It includes the special...

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Identifiers

PMID: 15781700
DOI: 10.1534/genetics.104.038612
PMCID: PMC1449722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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