Article
Investigating gene environment interaction in complex diseases: increasing power by selective sampling for environmental exposure.
International journal of epidemiology - 1 Dec 2007
Boks M P M, Schipper M, Schubart C D, Sommer I E, Kahn R S, Ophoff R A
Abstract excerpt
BACKGROUND: The often limited influence of disease associated alleles on the vulnerability to complex diseases has lead to increased interest in environmental interaction with genotype. However, gene environmental interactions (GEIs) are not easily studied, since high numbers of subjects are required to detect GEI. METHODS AND RESULTS: This study provides a potential useful method to increase the power of such...
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