Article
Binary trait mapping in experimental crosses with selective genotyping.
Genetics - 1 Jul 2009
Manichaikul Ani, Broman Karl W
Abstract excerpt
Selective genotyping is an efficient strategy for mapping quantitative trait loci. For binary traits, where there are only two distinct phenotypic values (e.g., affected/unaffected or present/absent), one may consider selective genotyping of affected individuals, while genotyping none or only some of the unaffected. If selective genotyping of this sort is employed, the usual method for binary trait mapping, which...
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