Joint tests for quantitative trait loci in experimental crosses.

doi:10.1186/1297-9686-36-6-601

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Article

Joint tests for quantitative trait loci in experimental crosses.

Genetics, selection, evolution : GSE - 1 Jan 2000

Beasley T Mark, Yang Dongyan, Yi Nengjun, Bullard Daniel C, Travis Elizabeth L, Amos Christopher I, Xu Shizhong, Allison David B

Abstract excerpt

Selective genotyping is common because it can increase the expected correlation between QTL genotype and phenotype and thus increase the statistical power of linkage tests (i.e., regression-based tests). Linkage can also be tested by assessing whether the marginal genotypic distribution conforms to its expectation, a marginal-based test. We developed a class of joint tests that, by constraining intercepts in...

Topics

Computer Simulation
Crosses, Genetic
Disease Transmission, Infectious
Genetics, Population
Humans
Linkage Disequilibrium
Mathematics
Models, Statistical
Phenotype
Quantitative Trait, Heritable
Selection, Genetic

Source

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Identifiers

PMID: 15496283
DOI: 10.1186/1297-9686-36-6-601
PMCID: PMC2697196

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