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Article

FXR promotes endothelial cell motility through coordinated regulation of FAK and MMP-9.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2009

Das Amitava, Yaqoob Usman, Mehta Dolly, Shah Vijay H

Abstract excerpt

OBJECTIVE: Farnesoid X Receptor (FXR) mediates important signaling functions of bile acids in diverse cell types including those residing in the vascular wall. Indeed, recent work has identified FXR as a potential regulator of vascular structure and function in part through transcriptional activation of MMP-9. However, the signal transduction pathways linking bile acids to changes in actin cytoskeleton that are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19150878
DOI: 10.1161/ATVBAHA.108.182725
PMCID: PMC2697392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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