Article
Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: role of CD81 and scavenger receptor class B type I and effect of antiviral drugs.
Hepatology (Baltimore, Md.) - 1 Feb 2009
Gottwein Judith M, Scheel Troels K H, Jensen Tanja B, Lademann Jacob B, Prentoe Jannick C, Knudsen Maria L, Hoegh Anne M, Bukh Jens
Abstract excerpt
UNLABELLED: Six major hepatitis C virus (HCV) genotypes and numerous subtypes have been described, and recently a seventh major genotype was discovered. Genotypes show significant molecular and clinical differences, such as differential response to combination therapy with interferon-alpha and ribavirin. Recently, HCV research has been accelerated by cell culture systems based on the unique growth capacity of...
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