Article
Hepatitis C virus infection in phenotypically distinct Huh7 cell lines.
PloS one - 10 Aug 2009
Sainz Bruno, Barretto Naina, Uprichard Susan L
Abstract excerpt
In 2005, the first robust hepatitis C virus (HCV) infectious cell culture system was developed based on the HCV genotype 2a JFH-1 molecular clone and the human-derived hepatoma cell line Huh7. Although much effort has been made to dissect and expand the repertoire of JFH-1-derived clones, less attention has been given to the host cell despite the intriguing facts that thus far only Huh7 cells have been found to...
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