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Article

Genetic and epigenetic events in human hepatocarcinogenesis (Review)

1 Jun 2001

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most frequently occurring liver carcinoma world-wide. Clinical and molecular medical analyses have produced a considerable amount of information about liver carcinogenesis. Loss of heterozygosity (LOH) analyses have revealed several chromosomal loci harboring potential tumor suppressors. These data support the idea that deletion or inactivation of tumor suppressors including...

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PMID: 11351262
DOI: 10.3892/ijo.18.6.1271

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