Article
The genetic and epigenetic alterations in human hepatocellular carcinoma: a recent update.
Protein & cell - 1 Sept 2014
Liu Ming, Jiang Lingxi, Guan Xin-Yuan
Abstract excerpt
Hepatocellular carcinoma (HCC) is one of the most frequent human malignancies worldwide with very poor prognosis. It is generally accepted that the progression of HCC is a long-term process with accumulation of multiple genetic and epigenetic alterations, which further lead to the activation of critical oncogenes or inactivation of tumor suppressor genes. HCC is characterized with multiple cancer hallmarks...
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