Article
Epigenetics in hepatocellular carcinoma: an update and future therapy perspectives.
World journal of gastroenterology - 14 Jan 2014
Ma Li, Chua Mei-Sze, Andrisani Ourania, So Samuel
Abstract excerpt
Hepatocellular carcinoma (HCC), the predominant form of adult liver malignancies, is a global health concern. Its dismal prognosis has prompted recent significant advances in the understanding of its etiology and pathogenesis. The deregulation of epigenetic mechanisms, which maintain heritable gene expression changes and chromatin organization, is implicated in the development of multiple cancers, including HCC....
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