Article
Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.
PLoS genetics - 1 Jan 2009
Deo Rahul C, Reich David, Tandon Arti, Akylbekova Ermeg, Patterson Nick, Waliszewska Alicja, Kathiresan Sekar, Sarpong Daniel, Taylor Herman A, Wilson James G
Abstract excerpt
Genome-wide association analysis in populations of European descent has recently found more than a hundred genetic variants affecting risk for common disease. An open question, however, is how relevant the variants discovered in Europeans are to other populations. To address this problem for cardiovascular phenotypes, we studied a cohort of 4,464 African Americans from the Jackson Heart Study (JHS), in whom we...
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