Article
Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.
American journal of human genetics - 6 Jun 2013
Coram Marc A, Duan Qing, Hoffmann Thomas J, Thornton Timothy, Knowles Joshua W, Johnson Nicholas A, Ochs-Balcom Heather M, Donlon Timothy A, Martin Lisa W, Eaton Charles B, Robinson Jennifer G, Risch Neil J, Zhu Xiaofeng, Kooperberg Charles, Li Yun, Reiner Alex P, Tang Hua
Abstract excerpt
Blood lipid concentrations are heritable risk factors associated with atherosclerosis and cardiovascular diseases. Lipid traits exhibit considerable variation among populations of distinct ancestral origin as well as between individuals within a population. We performed association analyses to identify genetic loci influencing lipid concentrations in African American and Hispanic American women in the Women's...
Topics
- Black or African American
- Aged
- Chromosomes, Human
- Female
- Genetic Loci
- Genome-Wide Association Study
- Hispanic or Latino
- Humans
- Lipids