Article
Resequencing of LPL in African Blacks and associations with lipoprotein-lipid levels.
European journal of human genetics : EJHG - 1 Sept 2015
Pirim Dilek, Wang Xingbin, Radwan Zaheda H, Niemsiri Vipavee, Bunker Clareann H, Barmada M Michael, Kamboh M Ilyas, Demirci F Yesim
Abstract excerpt
Genome-wide association studies have identified several loci associated with plasma lipid levels but those common variants together account only for a small proportion of the genetic variance of lipid traits. It has been hypothesized that the remaining heritability may partly be explained by rare variants with strong effect sizes. Here, we have comprehensively investigated the associations of both common and...
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