Article
A neomorphic sgs3 allele stabilizing miRNA cleavage products reveals that SGS3 acts as a homodimer.
The FEBS journal - 1 Feb 2009
Elmayan Taline, Adenot Xavier, Gissot Lionel, Lauressergues Dominique, Gy Isabelle, Vaucheret Hervé
Abstract excerpt
The putative RNA-binding protein SUPPRESSOR OF GENE SILENCING 3 (SGS3) protects RNA from degradation before transformation into dsRNA by the RNA-dependent RNA polymerase RDR6 during plant post-transcriptional gene silencing and trans-acting small interfering (siRNA) pathways. In this study, we show that SGS3 acts as a homodimer, and that the point mutation sgs3-3 impairs post-transcriptional gene silencing in a...
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