Article
Cytoplasmic and nuclear quality control and turnover of single-stranded RNA modulate post-transcriptional gene silencing in plants.
Nucleic acids research - 1 Apr 2013
Moreno Ana Beatriz, Martínez de Alba Angel Emilio, Bardou Florian, Crespi Martin D, Vaucheret Hervé, Maizel Alexis, Mallory Allison C
Abstract excerpt
Eukaryotic RNA quality control (RQC) uses both endonucleolytic and exonucleolytic degradation to eliminate dysfunctional RNAs. In addition, endogenous and exogenous RNAs are degraded through post-transcriptional gene silencing (PTGS), which is triggered by the production of double-stranded (ds)RNAs and proceeds through short-interfering (si)RNA-directed ARGONAUTE-mediated endonucleolytic cleavage. Compromising...
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