Article
DRB4-dependent TAS3 trans-acting siRNAs control leaf morphology through AGO7.
Current biology : CB - 9 May 2006
Adenot Xavier, Elmayan Taline, Lauressergues Dominique, Boutet Stéphanie, Bouché Nicolas, Gasciolli Virginie, Vaucheret Hervé
Abstract excerpt
trans-acting siRNAs (ta-siRNAs) are endogenous RNAs that direct the cleavage of complementary mRNA targets . TAS gene transcripts are cleaved by miRNAs; the cleavage products are protected against degradation by SGS3, copied into dsRNA by RDR6, and diced into ta-siRNAs by DCL4 . We describe hypomorphic rdr6 and sgs3 Arabidopsis mutants, which do not exhibit the leaf developmental defects observed in null mutants...
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