Article
Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach.
Diabetes, obesity & metabolism - 1 Feb 2009
McKinnon E, Morahan G, Nolan D, James I
Abstract excerpt
AIM: The Major Histocompatibility Complex (MHC) is a highly polymorphic region on chromosome 6 encompassing the human leucocyte antigen (HLA)-DQ/DR loci most predictive of susceptibility to type 1 diabetes (T1D). To assess the contribution of other MHC genes, in this exploratory analysis of Type 1 Diabetes Genetics Consortium (T1DGC) family data we characterize association between susceptibility and MHC single...
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