Article
Use of class I and class II HLA loci for predicting age at onset of type 1 diabetes in multiple populations.
Diabetologia - 1 Sept 2012
Valdes A M, Erlich H A, Carlson J, Varney M, Moonsamy P V, Noble J A
Abstract excerpt
AIMS/HYPOTHESIS: The study aimed to assess, in multiple populations, the role of HLA alleles on early and late age at onset of type 1 diabetes. METHODS: Stepwise linear regression models were used to determine which HLA class I and class II risk alleles to include. High-resolution genotyping data for patients from the Type 1 Diabetes Genetics Consortium (T1DGC) collection (n = 2,278) and four independent cohorts...
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