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Article

Cyclin D1 and cancer development in laryngeal premalignancy patients.

Cancer prevention research (Philadelphia, Pa.) - 1 Jan 2009

Papadimitrakopoulou Vassiliki, Izzo Julie G, Liu Diane D, Myers Jeffrey, Ceron Tania L, Lewin Jan, William William N, Atwell Anthea, Lee J Jack, Gillenwater Ann, El-Naggar Adel, Wu Xifeng, Lippman Scott M, Hittelman Walter N, Hong Waun Ki

Abstract excerpt

In a previous trial, we found that combined 13-cis-retinoic acid, IFN-alpha, and alpha-tocopherol more effectively reversed advanced premalignant lesions of the larynx than of the oral cavity and that cyclin D1 (CD1) G/A870 single nucleotide polymorphism correlated with cancer risk. We conducted the present trial primarily to confirm the clinical activity of the combination in advanced laryngeal premalignancy and...

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Identifiers

PMID: 19139013
DOI: 10.1158/1940-6207.CAPR-08-0111
PMCID: PMC4243520

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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