Article
Cyclin D1 gene polymorphism as a risk factor for oral premalignant lesions.
Carcinogenesis - 1 Oct 2006
Huang Maosheng, Spitz Margaret R, Gu Jian, Lee J Jack, Lin Jie, Lippman Scott M, Wu Xifeng
Abstract excerpt
BACKGROUND: Deregulation of cell cycle plays an important role in tumorigenesis. Cyclin D1 gene (CCND1) is a key regulator of the G(1) phase of the cell cycle. METHODS: In this case-control study of 115 oral premalignant lesion (OPL) patients and 230 controls, we genotyped the CCND1 single nucleo...
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