Article
TRPM2 variants and bipolar disorder risk: confirmation in a family-based association study.
Bipolar disorders - 1 Feb 2009
Xu Chun, Li Peter P, Cooke Robert G, Parikh Sagar V, Wang KeSheng, Kennedy James L, Warsh Jerry J
Abstract excerpt
OBJECTIVE: Recent case-control studies implicate the transient receptor potential melastatin 2 (TRPM2) channel in conferring risk for bipolar disorder (BD), though the risk variants differed. As confounding effects of population structure could not be unequivocally ruled out as the basis for the discordance, we tested the association of TRPM2 with BD in a family design, which is immune to population...
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