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Article

Association of the iPLA2β gene with bipolar disorder and assessment of its interaction with TRPM2 gene polymorphisms.

Psychiatric genetics - 1 Apr 2013

Xu Chun, Warsh Jerry J, Wang Keng S, Mao Chun X, Kennedy James L

Abstract excerpt

Altered intracellular calcium homeostasis and oxidative stress are involved in the pathophysiology of bipolar disorder (BD)-I. To explore the genes contributing to these abnormalities, we examined the association with BD of the iPLA2β (PLA2G6), a signaling enzyme that mobilizes the arachidonic acid signaling cascade and activates oxidative stress, and assessed whether it interacts genetically with type 2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23277130
DOI: 10.1097/YPG.0b013e32835d700d

Genes

TRPM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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