Article
Independent replications and integrative analyses confirm TRANK1 as a susceptibility gene for bipolar disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 May 2021
Li Wenqiang, Cai Xin, Li Hui-Juan, Song Meng, Zhang Chu-Yi, Yang Yongfeng, Zhang Luwen, Zhao Lijuan, Liu Weipeng, Wang Lu, Shao Minglong, Zhang Yan, Zhang Chen, Cai Jun, Zhou Dong-Sheng, Li Xingxing, Hui Li, Jia Qiu-Fang, Qu Na, Zhong Bao-Liang, Zhang Shu-Fang, Chen Jing, Xia Bin, Li Yi, Song Xueqin, Fan Weixing, Tang Wei, Tang Wenxin, Tang Jinsong, Chen Xiaogang, Yue Weihua, Zhang Dai, Fang Yiru, Xiao Xiao, Li Ming, Lv Luxian, Chang Hong
Abstract excerpt
Genetic analyses for bipolar disorder (BD) have achieved prominent success in Europeans in recent years, whereas its genetic basis in other populations remains relatively less understood. We herein report that the leading risk locus for BD in European genome-wide association studies (GWAS), the single-nucleotide polymorphism (SNP) rs9834970 near TRANK1 at 3p22 region, is also genome-wide significantly associated...
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