Article
Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
Molecular psychiatry - 1 Feb 2013
Chen D T, Jiang X, Akula N, Shugart Y Y, Wendland J R, Steele C J M, Kassem L, Park J-H, Chatterjee N, Jamain S, Cheng A, Leboyer M, Muglia P, Schulze T G, Cichon S, Nöthen M M, Rietschel M, McMahon F J, Farmer A, McGuffin P, Craig I, Lewis C, Hosang G, Cohen-Woods S, Vincent J B, Kennedy J L, Strauss J
Abstract excerpt
Meta-analyses of bipolar disorder (BD) genome-wide association studies (GWAS) have identified several genome-wide significant signals in European-ancestry samples, but so far account for little of the inherited risk. We performed a meta-analysis of ∼750,000 high-quality genetic markers on a combined sample of ∼14,000 subjects of European and Asian-ancestry (phase I). The most significant findings were further...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.