Article
Association study of Wnt signaling pathway genes in bipolar disorder.
Archives of general psychiatry - 1 Jul 2008
Zandi Peter P, Belmonte Pamela L, Willour Virginia L, Goes Fernando S, Badner Judith A, Simpson Sylvia G, Gershon Elliot S, McMahon Francis J, DePaulo J Raymond, Potash James B
Abstract excerpt
CONTEXT: The Wnt signaling pathways promote cell growth and are best known for their role in embryogenesis and cancer. Several lines of evidence suggest that these pathways might also be involved in bipolar disorder. OBJECTIVE: To test for an association between candidate genes in the Wnt signaling pathways and disease susceptibility in a family-based bipolar disorder study. DESIGN: Two hundred twenty-seven...
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