Article
Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma.
Allergy - 1 Apr 2009
Wu H, Romieu I, Sienra-Monge J-J, Li H, del Rio-Navarro B E, London S J
Abstract excerpt
BACKGROUND: A genome-wide association study identified ORM1-like 3 (orosomucoid 1-like 3, ORMDL3) as an asthma candidate gene. Single nucleotide polymorphisms (SNPs) in the region including ORMDL3 on chromosome 17q21 were related to childhood asthma risk and ORMDL3 expression levels in Europeans. OBJECTIVE: We examined whether polymorphisms in ORMDL3 and the adjacent gasdermin-like (GSDML) gene associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.