Article
Solution structure of the NaV1.2 C-terminal EF-hand domain.
The Journal of biological chemistry - 6 Mar 2009
Miloushev Vesselin Z, Levine Joshua A, Arbing Mark A, Hunt John F, Pitt Geoffrey S, Palmer Arthur G
Abstract excerpt
Voltage-gated sodium channels initiate the rapid upstroke of action potentials in many excitable tissues. Mutations within intracellular C-terminal sequences of specific channels underlie a diverse set of channelopathies, including cardiac arrhythmias and epilepsy syndromes. The three-dimensional...
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