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Article

Genotyping of alpha-thalassemia deletions using multiplex polymerase chain reactions and gold nanoparticle-filled capillary electrophoresis.

Journal of chromatography. A - 13 Feb 2009

Chen Yen-Ling, Shih Chi-Jen, Ferrance Jerome, Chang Ya-Sian, Chang Jan-Gowth, Wu Shou-Mei

Abstract excerpt

A gold nanoparticle-filled capillary electrophoresis method combined with three multiplex polymerase chain reactions (PCRs) was established for simultaneous diagnosis of five common alpha-thalassemia deletions, including the -alpha(3.7) deletion, -alpha(4.2) deletion, Southeast Asian (--(SEA)), Filipino (--(FIL)) and Thai (--(THAI)) deletions. Gold nanoparticles (GNPs) were used as a pseudostationary phase to...

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Identifiers

PMID: 19128803
DOI: 10.1016/j.chroma.2008.12.027

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SEA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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