Article
Genotyping of single nucleotide polymorphism by probe-gated silica nanoparticles.
Analytical biochemistry - 15 Nov 2017
Ercan Meltem, Ozalp Veli C, Tuna Bilge G
Abstract excerpt
The development of simple, reliable, and rapid approaches for molecular detection of common mutations is important for prevention and early diagnosis of genetic diseases, including Thalessemia. Oligonucleotide-gated mesoporous nanoparticles-based analysis is a new platform for mutation detection that has the advantages of sensitivity, rapidity, accuracy, and convenience. A specific mutation in β-thalassemia, one...
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