Article
Gold nanoparticle-based electrophoresis-free colorimetric detection method for allele-specific PCR-SNP genotyping.
Analytical biochemistry - 1 Sept 2026
Verma Surya Kant, Kumar Lal Krishan, Mitra Murli Dhar, Kumar Jitendra, Singh Prashant, Mohiddin Roshan, Nayan Varij, Singh Dheer, Onteru Suneel Kumar
Abstract excerpt
Conventional allele specific PCR (AS-PCR) genotyping using gel electrophoresis and ethidium bromide (EtBr) is costly, particularly in developing countries. It also poses health risks to working personnel as it requires specialized equipment and toxic dyes like EtBr. Hence, the present study developed a simple and cost-effective colorimetric genotyping method using gold nanoparticles solution (AuNPs) and...
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