Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q.

doi:10.1194/jlr.M800515-JLR200

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q.

Journal of lipid research - 1 May 2009

Ober Carole, Nord Alex S, Thompson Emma E, Pan Lin, Tan Zheng, Cusanovich Darren, Sun Ying, Nicolae Raluca, Edelstein Celina, Schneider Daniel H, Billstrand Christine, Pfaffinger Ditta, Phillips Natasha, Anderson Rebecca L, Philips Binu, Rajagopalan Ramakrishnan, Hatsukami Thomas S, Rieder Mark J, Heagerty Patrick J, Nickerson Deborah A, Abney Mark, Marcovina Santica, Jarvik Gail P, Scanu Angelo M, Nicolae Dan L

Abstract excerpt

Plasma lipoprotein(a) (Lp[a]) level is an independent risk factor of cardiovascular disease that is under strong genetic control. We conducted a genome-wide association study of plasma Lp(a) in 386 members of a founder population that adheres to a communal lifestyle, proscribes cigarette smoking, and prepares and eats meals communally. We identified associations with 77 single nucleotide polymorphisms (SNPs)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 6

Share to Enhancer Elements, Genetic

Share to Kringles

Share to Linkage Disequilibrium

Share to Lipoprotein(a)

Share to Protein Isoforms

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 19124843
DOI: 10.1194/jlr.M800515-JLR200
PMCID: PMC2666166

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q.PMID 19124843Read ↗

Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels.Semantic proximity Read ↗

Genome- and exome-wide association study of serum lipoprotein (a) in the Jackson Heart Study.Semantic proximity Read ↗

Genetic variants associated with Lp(a) lipoprotein level and coronary disease.Semantic proximity Read ↗

Genetics and Pathophysiological Mechanisms of Lipoprotein(a)-Associated Cardiovascular Risk.Semantic proximity Read ↗

A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.Semantic proximity Read ↗

Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans.Semantic proximity Read ↗

Lipoprotein(a) beyond the kringle IV repeat polymorphism: The complexity of genetic variation in the LPA gene.Semantic proximity Read ↗

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestriesSemantic proximity Read ↗

Genetic variation in LPAL2, LPA, and PLG predicts plasma lipoprotein(a) level and carotid artery disease risk.Semantic proximity Read ↗

Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts.Semantic proximity Read ↗

Structure-guided dissection of the genetic variations within human LPA locus and its role in the development of cardiovascular diseases.Semantic proximity Read ↗

Three single-nucleotide polymorphisms in LPA account for most of the increase in lipoprotein(a) level elevation in African Americans compared with European Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.