Article
Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts.
Atherosclerosis - 1 Aug 2011
Zabaneh Delilah, Kumari Meena, Sandhu Manj, Wareham Nick, Wainwright Nick, Papamarkou Theodore, Hopewell Jemma, Clarke Robert, Li KaWah, Palmen Jutta, Talmud Philippa J, Kronenberg Florian, Lamina Claudia, Summerer Monika, Paulweber Bernhard, Price Jackie, Fowkes Gerry, Stewart Marlene, Drenos Fotios, Shah Sonia, Shah Tina, Casas Juan-Pablo, Kivimaki Mika, Whittaker John, Hingorani Aroon D, Humphries Steve E
Abstract excerpt
BACKGROUND: Both genome-wide association studies and candidate gene studies have reported that the major determinant of plasma levels of the Lipoprotein (a) [Lp(a)] reside within the LPA locus on chromosome 6. We have used data from the HumanCVD BeadChip to explore the contribution of other candidate genes determining Lp(a) levels. METHODS: 48,032 single nucleotide polymorphisms (SNPs) from the Illumina HumanCVD...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
