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Article

Genetic variation in LPAL2, LPA, and PLG predicts plasma lipoprotein(a) level and carotid artery disease risk.

Stroke - 1 Jan 2011

Ronald James, Rajagopalan Ramakrishnan, Cerrato Felecia, Nord Alex S, Hatsukami Thomas, Kohler Ted, Marcovina Santica, Heagerty Patrick, Jarvik Gail P

Abstract excerpt

BACKGROUND AND PURPOSE: lipoprotein(a) [Lp(a)] level is an established risk factor for coronary artery disease and has been implicated in carotid artery disease (CAAD). The relationship between genetic variation in the LPA gene region and CAAD risk remains unknown. METHODS: we genotyped single nucleotide polymorphisms (SNPs) in the LPAL2, LPA, and PLG regions in 530 individuals with severe CAAD and 770 controls...

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Identifiers

PMID: 21127300
DOI: 10.1161/STROKEAHA.110.591230
PMCID: PMC3020902

Genes

LPA
PLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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