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Article

Genetic variants associated with Lp(a) lipoprotein level and coronary disease.

The New England journal of medicine - 24 Dec 2009

Clarke Robert, Peden John F, Hopewell Jemma C, Kyriakou Theodosios, Goel Anuj, Heath Simon C, Parish Sarah, Barlera Simona, Franzosi Maria Grazia, Rust Stephan, Bennett Derrick, Silveira Angela, Malarstig Anders, Green Fiona R, Lathrop Mark, Gigante Bruna, Leander Karin, de Faire Ulf, Seedorf Udo, Hamsten Anders, Collins Rory, Watkins Hugh, Farrall Martin

Abstract excerpt

BACKGROUND: An increased level of Lp(a) lipoprotein has been identified as a risk factor for coronary artery disease that is highly heritable. The genetic determinants of the Lp(a) lipoprotein level and their relevance for the risk of coronary disease are incompletely understood. METHODS: We used a novel gene chip containing 48,742 single-nucleotide polymorphisms (SNPs) in 2100 candidate genes to test for...

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Source

Identifiers

PMID: 20032323
DOI: 10.1056/NEJMoa0902604

Genes

LPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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