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Article

TNFSF15 transcripts from risk haplotype for Crohn's disease are overexpressed in stimulated T cells.

Human molecular genetics - 15 Mar 2009

Kakuta Yoichi, Ueki Nobuo, Kinouchi Yoshitaka, Negoro Kenichi, Endo Katsuya, Nomura Eiki, Takagi Sho, Takahashi Seiichi, Shimosegawa Tooru

Abstract excerpt

TNFSF15 is a susceptibility gene for Crohn's disease (CD). It remains to be elucidated how the associated single nucleotide polymorphisms (SNPs) in TNFSF15 affect the susceptibility to CD. Because there are no non-synonymous SNPs in TNFSF15, we speculated that one or more of the SNPs associated with CD may act as cis-regulatory SNPs. To reveal the effects of the SNPs on the transcriptional activity of TNFSF15, we...

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Identifiers

PMID: 19124533
DOI: 10.1093/hmg/ddp005

Genes

TNFSF15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TNFSF15 transcripts from risk haplotype for Crohn's disease are overexpressed in stimulated T cells.PMID 19124533Read ↗

Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.Semantic proximity Read ↗

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Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy.Semantic proximity Read ↗

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