Article
Contribution of TNFSF15 gene variants to Crohn's disease susceptibility confirmed in UK population.
Inflammatory bowel diseases - 1 Jun 2008
Tremelling Mark, Berzuini Carlo, Massey Dunecan, Bredin Francesca, Price Catherine, Dawson Claire, Bingham Sheila A, Parkes Miles
Abstract excerpt
BACKGROUND: Identification of Crohn's disease (CD)-associated genetic variants is key to understanding pathogenic pathways underlying disease susceptibility. Recent reports of an association between TNFSF15 variants and CD have been modestly replicated in European populations, suggesting heterogeneity at this locus with stronger CD association in Japanese than European populations. METHODS: We investigated the...
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