Article
Association of TNFSF15 with Crohn's disease in Koreans.
The American journal of gastroenterology - 1 Jun 2008
Yang Suk-Kyun, Lim Jiyoung, Chang Hye-Sook, Lee Inchul, Li Yuqing, Liu Jianjun, Song Kyuyoung
Abstract excerpt
OBJECTIVES: A recent genomewide association study from a Japanese population identified tumor necrosis factor superfamily member 15 (TNFSF15) as an inflammatory bowel disease gene. Previous studies have shown that expression of TNFSF15 was upregulated in macrophages and lymphocytes of the intestinal lamina propria of Crohn's disease (CD) patients. Here, we have tested four single nucleotide polymorphisms (SNPs)...
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