Article
TNFSF15 polymorphisms are associated with susceptibility to inflammatory bowel disease in a new European cohort.
The American journal of gastroenterology - 1 Feb 2009
Thiébaut R, Kotti S, Jung C, Merlin F, Colombel J F, Lemann M, Almer S, Tysk C, O'Morain M, Gassull M, Binder V, Finkel Y, Pascoe L, Hugot J-P
Abstract excerpt
OBJECTIVES: Inflammatory bowel disease (IBD), e.g., Crohn's disease (CD) and ulcerative colitis (UC), is a complex genetic disorder. Tumor necrosis factor (ligand) superfamily, member 15 (TNFSF15) has been previously identified as a susceptibility gene for CD in Japanese and UK cohorts. This replication study was designed in order to confirm and further validate the role of TNFSF15 in IBD. METHODS: A total of 666...
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